Paclitaxel yog ib tug complex natural khoom uas muaj zog antitumor kev ua si.Vim qhov tshwj xeeb thiab complexity ntawm nws cov qauv.it yog ib qho tseem ceeb kom nruj me ntsis tswj qhov zoo thiab cov qauv ntawmpaclitaxel.Kev tswj xyuas zoo thiab cov qauv rau paclitaxel tau piav qhia hauv qab no.
Kev tswj xyuas zoo ntawm paclitaxel
1.raw khoom tswj: cov khoom siv raw ntawm paclitaxel yuav tsum tau yuav los ntawm cov neeg muag khoom tsim nyog.and xyuas kom meej purity thiab zoo ntawm raw cov ntaub ntawv.Raw cov ntaub ntawv yuav tsum raug nruj zoo soj ntsuam.xws li tshuaj ntsuam xyuas.microbial detection.impurity detection.etc. .kom paub meej tias lawv ua tau raws li qhov yuav tsum tau ua.
2.kev tswj cov txheej txheem: Hauv cov txheej txheem tsim khoom ntawm paclitaxel. nruj tswj kev ntsuas yuav tsum tau ua.nrog rau cov txheej txheem verification.critical control point monitoring.intermediate testing.etc..los xyuas kom meej qhov ruaj khov ntawm cov txheej txheem ntau lawm thiab cov khoom sib xws.
3. Kev tshuaj xyuas cov khoom tiav:paclitaxelcov khoom yuav tsum yog cov kev soj ntsuam zoo.including traits.purity.content.related substances.solvent residues thiab lwm yam khoom los xyuas kom meej cov khoom muaj kev ruaj ntseg thiab zoo.
4.stability soj ntsuam: paclitaxel cov khoom yuav tsum yog lub sij hawm ntev stability tshuaj ntsuam xyuas lawv cov kev hloov zoo nyob rau hauv txawv cia tej yam kev mob.to muab lub hauv paus rau lub validity ntawm cov khoom.
Standard ntawm paclitaxel
1.Txoj kev txiav txim siab: paclitaxel cov ntsiab lus kev txiav txim siab feem ntau suav nrog kev ua haujlwm siab ua kua chromatography.ultraviolet pom spectrophotometry thiab lwm yam.Strict internal control standards yuav tsum raug tsim los xyuas kom meej tias cov ntsiab lus ntawm txhua pawg ntawm cov khoom ua tau raws li cov kev cai.
2.Kev tshuaj xyuas cov khoom muaj feem xyuam: cov tshuaj muaj feem xyuam ntawm paclitaxel feem ntau suav nrog nws cov khoom siv metabolites thiab cov khoom decomposition. Cov txheej txheem thiab cov qauv rau kev tshuaj xyuas cov khoom muaj feem xyuam yuav tsum raug tsim los xyuas kom meej tias cov ntsiab lus ntawm cov khoom muaj feem xyuam hauv cov khoom tiav nyob rau hauv qhov kev teev tseg.
3.solvent residue check: Organic solvents yuav siv tau rau hauv cov txheej txheem ntawm paclitaxel.so cov khoom tiav yuav tsum tau kuaj xyuas cov kuab tshuaj residue kom ua raws li cov kev cai.
4.lwm cov khoom soj ntsuam: Ntxiv rau cov khoom soj ntsuam saum toj no.lwm yam khoom yuav tsum tau kuaj xyuas raws li cov khoom zoo.xws li particle size distribution.pH value.moisture.etc.
Cov ntsiab lus
Raws li ib qho tseem ceeb los tiv thaiv qog noj tshuaj.kev tswj kom zoo thiab tus qauv ntawmpaclitaxelyog qhov tseem ceeb heev rau kev nyab xeeb thiab kev ua tau zoo ntawm cov khoom.Strict zoo tswj kev ntsuas yuav tsum tau ua nyob rau hauv cov txheej txheem ntau lawm los tsim cov qauv kev tshawb fawb thiab tsim nyog los xyuas kom meej tias qhov zoo ntawm txhua batch ntawm cov khoom yog ruaj khov thiab txhim khu kev qha. Tib lub sijhawm .kev saib xyuas yuav tsum muaj zog ntxiv kom muaj kev nyab xeeb thiab ua raws li kev tsim khoom thiab siv.Los ntawm kev txhim kho txuas ntxiv thiab txhim kho cov qauv kev tswj xyuas zoo. qhov kev tsim khoom zoo thiab cov neeg mob siv cov paclitaxel tuaj yeem txhim kho ntxiv.
Nco tseg: Cov txiaj ntsig zoo thiab cov ntawv thov tau nthuav tawm hauv kab lus no yog muab los ntawm cov ntaub ntawv luam tawm.
Post lub sij hawm: Nov-16-2023