Yew taxus chinensis extract yog muab rho tawm los ntawm cov nroj tsuag tsis tshua muaj, nteg, qia, tawv nqaij, hauv paus muaj cov khoom xyaw tseem ceeb yog: yew alkali diterpenoid tebchaw, yew ning A thiab yew, yew ning H, yew, yew ning K, l, yew alkali, jinsong daj ketone, txoj kab nqes uas tawm A, qhov no tawm ketone ketone, jinsong ob lub daj ketone, naphtha, yew, polysaccharide, tannins, tanned liab, thiab lwm yam., kuj muaj lwm yam polyphenols, amino acids, ntoo resin, inorganic ntsiab. Paclitaxel muaj anti-leukemia thiab qog cov teebmeem.
Paclitaxel, uas peb tab tom tham txog, yog cov tshuaj zoo tshaj plaws los tiv thaiv kab mob qog noj ntshav uas tau pom nyob rau tam sim no.Nws tau siv dav hauv kev kho mob qog noj ntshav, qog noj ntshav ntawm zes qe menyuam, mob taub hau thiab caj dab, mob ntsws cancer thiab ntau yam. lwm yam mob qog noj ntshav kho mob.
Ntuj Paclitaxel vs Semi-synthetic Paclitaxel
Cov impurities:
Ntuj paclitaxelyog muab rho tawm los ntawm cov hauv paus hniav, stems thiab nplooj ntawm Taxus chinensis.Tom qab kem chromatography thiab recrystallization, tag nrho cov txheej txheem yog lub cev extraction thiab purification yam tsis muaj tshuaj tiv thaiv.Cov impurities muaj nyob rau hauv nws yog los ntawm cov khoom xyaw ntawm cov nroj tsuag nws tus kheej, thiab tsis muaj impurities. coj los ntawm cov tshuaj synthesis.Yog li ntawd, lub impurity fixation ntawm ntuj paclitaxel yog kawm tag nrho thiab ntau controllable tam sim no.
Semi-synthetic paclitaxelmuaj cov tshuaj synthesis ntau dua li cov txheej txheem hauv nws cov txheej txheem, thiab nws cov impurity qhov chaw kuj tseem muaj ntau tshaj li cov khoom ntuj tsim, suav nrog qee qhov muab rho tawm los ntawm cov nroj tsuag, thiab qee qhov impurities generated los ntawm cov tshuaj synthesis tshuaj. Muaj peev xwm impurities.Nyob rau hauv cov txheej txheem no, qhov ntau thiab hom impurities yog tas li hloov. Yog li ntawd, semi-synthetic paclitaxel muaj tsawg controllability nyob rau hauv impurities, thiab tshiab impurities yuav tsum tau kawm tas li nyob rau hauv cov txheej txheem ntau lawm.Impurities tsim los ntawm ntau lawm txheej txheem kuj tseem. sib txawv heev, thiab kev tsom xam tshwj xeeb yog yuav tsum tau.
Yunnan Hande Bio-Tech tau koom nrog hauv kev rho tawm thiab txhim kho cov se rau 30 xyoo, thiab nws cov khoom tseem ceeb yogntuj paclitaxel,10-DAB semi-synthetic paclitaxel, 10-deacetylbaccatin III, docetaxel, cabazitaxel, thiab lwm yam Yog xav paub ntxiv txog paclitaxel APIs, thov hu rau peb !!! (Whatsapp / Wechat: + 86 18187887160)
Post lub sij hawm: Jan-19-2023