Khoom Siv Tshuaj
Paclitaxel, raws li cov tshuaj tiv thaiv kab mob, yog dav siv nyob rau hauv ntau yam Txhaj tshuaj thiab Devices.
Nws yog tsim los ntawm natural extraction thiab synthesis.
Raws li cov nroj tsuag ntawm ib txwm muab rho tawm paclitaxel, Taxus Chinensis, kuj tsis tshua muaj thiab muaj lub voj voog loj hlob ntev, cov txheej txheem ntawm kev sib txuas tau maj mam muab los ntawm paclitaxel los ntawm kev tshawb fawb thiab kev sim thoob ntiaj teb, suav nrog tag nrho cov synthesis, semi-synthesis, thiab endophytic synthesis.
Vim txoj kev siv tshuaj lom neeg ntev, ntau cov txheej txheem synthesis, thiab nyuaj rau kev tswj cov tshuaj tiv thaiv kab mob, tag nrho cov paclitaxel synthesized yuav tsum siv cov tshuaj reagents kim dua, thiab cov tawm los kuj tsawg, uas tsis haum rau cov khoom loj thiab kev lag luam hauv dav dav.
Yog li ntawd, qhov loj ntawm paclitaxel nyob rau hauv kev ua lag luam feem ntau yog tsim los ntawm natural extraction ntawm cultivated taxus thiab semi-synthetic txoj kev.
Ntuj Paclitaxel vs Semi-synthetic Paclitaxel
Ntu 1: Cov txheej txheem tsim khoom
-Raw khoom: Artificially cog Yew
-Extraction txheej txheem: raw khoom + kem chromatography + recrystallization = cov khoom tiav
-Extraction txheej txheem: lub cev cov tshuaj tiv thaiv, tsis muaj tshuaj synthesis txheej txheem
-Raw khoom: Artificially cog Yew
-Extraction txheej txheem: raw khoom + tshuaj reagent cov tshuaj tiv thaiv + concentrated crystallization + ntau yam tshuaj tiv thaiv + recrystallization = cov khoom tiav
-Extraction txheej txheem: tshuaj tiv thaiv
Nyob rau hauv cov nqe lus ntawm technology, natural paclitaxel muaj yooj yim extraction cov kauj ruam piv nrog semi-synthetic paclitaxel thiab ntau zoo dua semi-synthetic paclitaxel nyob rau hauv cov nqe lus ntawm stability thiab kev nyab xeeb, thaum semi-synthetic paclitaxel txo tus nqi ntawm cov khoom tsim nyob rau hauv cov nqe lus ntawm cov nqi thiab raw khoom. , thiab tseem txhim kho qee qhov teeb meem tshwm sim los ntawm qhov tsis txaus ntawm cov khoom siv hauv khw.
Piv nrog rau ob txoj kev tsim paclitaxel, ntuj paclitaxel muaj kev ruaj ntseg zoo dua thiab kev nyab xeeb hauv cov khoom siv kho mob, uas yog ib qho laj thawj vim li cas cov tuam txhab kho mob feem ntau hauv kev ua lag luam siv cov paclitaxel ntuj ua raw khoom.
Yunnan Hande Biotechnology Co., Ltd. tau koom nrog hauv kev rho tawm thiab kev txhim kho ntawm taxanes rau 30 xyoo, thiab nws cov khoom tseem ceeb yog ntuj paclitaxel, 10-DAB semi-synthetic paclitaxel, 10-deacetylbaccatin III, docetaxel, cabazitaxel, thiab lwm yam. Xav paub ntau ntxiv txog paclitaxel APIs, thov hu rau peb !!! (Whatsapp / Wechat: +86 18187887160)
Post lub sij hawm: Jan-17-2023