Qhov zoo ntawm Albumin-bound paclitaxel

Paclitaxel yog ib qho ntawm peb cov tshuaj khomob classic, tab sis nws cov dej solubility tsis zoo thiab nws yuav tsum tau yaj nrog cov kuab tshuaj organic.Albumin-bound paclitaxel siv nanotechnology los ua kom cov tshuaj xa thiab bioavailability ntawm paclitaxel nrog kev pab los ntawm ntuj albumin.Qhov no tsis tsuas yog zam qhov tsis hnov ​​​​tsw / toxicity tshwm sim los ntawm cov kuab tshuaj organic, tab sis kuj tsis xav tau cov tshuaj hormone pretreatment; Nws tseem tuaj yeem ua rau albumin nqa paclitaxel tawm ntawm cov ntshav ncig sai dua, dhau los ntawm cov kab mob endothelial los ntawm receptor mediated endocytosis, thiab ntxiv dag zog rau cov qog nqaij hlav. los ntawm lub siab permeability thiab tuav nyhuv (EPR nyhuv) ntawm cov qog, uas txuas ntxiv mus qhia pharmacokinetic zoo.

Nyob rau hauv lub sijhawm ntawm kev siv tshuaj tiv thaiv kab mob, kev ua tau zoo ntawm cov tshuaj ib leeg tsis txaus, thiab lub hom phiaj tshem tawm tus nqi (ORR) ntawm ib qho tshuaj tsis pub tshaj 20%; Yuav ua li cas nthuav cov neeg tau txais txiaj ntsig ntawm kev siv tshuaj tiv thaiv kab mob, kev kho ua ke yuav yog ib qho kev daws teeb meem zoo, ntawm cov uas hom kev siv tshuaj khomob ua ke yog qhov kub ntawm kev tshawb nrhiav tam sim no.

Los ntawm qhov kev xav no, Albumin-bound paclitaxel muaj nws tus kheej qhov zoo, nws ORR siab dua, nws tuaj yeem tua cov qog hlwb zoo dua, thiab txhawb kev nthuav tawm cov qog antigen; Tsis muaj cov tshuaj hormone pretreatment yog xav tau kom tsis txhob muaj kev tiv thaiv kab mob; Cov qog nqaij hlav ntau dua ntxiv txo kev puas tsuaj rau cov ntaub so ntswg.

Nco tseg: Cov peev txheej ua tau zoo thiab cov ntawv thov tau qhia hauv kab lus no yog tag nrho los ntawm cov ntaub ntawv luam tawm.

Yunnan Hande Biotechnology Co., Ltd tau tshwj xeeb hauv kev tsim khoom ntawmPaclitaxel APIrau ntau tshaj 20 xyoo, thiab yog ib lub ntiaj teb kev ywj pheej manufacturers ntawm paclitaxel API, ib tsob nroj-derived tshuaj tiv thaiv kab mob cancer, pom zoo los ntawm US FDA, Teb chaws Europe EDQM, Australian TGA, Suav CFDA, Is Nrias teb, Nyiv thiab lwm lub teb chaws cov koom haum tswj. .Hande muaj peev xwm muab tsis tau tsuas yog high-zoopaclitaxel raw cov ntaub ntawv, tab sis kuj muaj kev txawj hloov cov kev pab cuam ntsig txog paclitaxel formulation.Yog xav paub ntxiv, thov hu rau peb ntawm 18187887160.